Nuclear Physics and Atomic Energy

Ядерна фізика та енергетика
Nuclear Physics and Atomic Energy

  ISSN: 1818-331X (Print), 2074-0565 (Online)
  Publisher: Institute for Nuclear Research of the National Academy of Sciences of Ukraine
  Languages: Ukrainian, English
  Periodicity: 4 times per year

  Open access peer reviewed journal

 Home page   About 
Nucl. Phys. At. Energy 2000, volume 1, issue 2, pages 150-156.
Section: Radioecology and Radiobiology.
Published online: 30.12.2000.
PDF Full text (ua)
https://doi.org/10.15407/jnpae2000.02.150

Reaction of haemopoietic system of animals on the additional internal irradiation

N. K. Rodionova1, A. I. Lipska1, I. Yu. Nikitina1, L. B. Pinchuk2

1R. E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine
2Institute for Nuclear Research of the National Academy of Sciences of Ukraine, Kyiv, Ukraine

Abstract: The investigation was carried out using rats of the Vistar line, which were exposed to prolongated internal irradiation. Three animal groups were irradiated with different radiation loads. The following changes in bone marrow system (BMS) were investigated: the number of erythrocytes, leukocytes, trombocytes, leukogram of cells in marrow, mitotic activity. The same way of BMS changes was determined, but the expression of these changes increased according to the doses of irradiation. The qualitative changes were observed before quantitative changes. It was determined, that disturbances in BMS are caused by incorporated osteotropic radionuclides and they can be taken into account as the unfavorable indices for forecasting the diseases of blood system.

References:

1. Lajtha L. G. Brit. J. Haemat. 29 (1975) 529. https://doi.org/10.1111/j.1365-2141.1975.tb02739.x

2. Коноплянников А. Г. Радиобиология стволовых клеток (Москва: Энергоатомиздат, 1984) 120 с.

3. Отдаленные последствия поражений, вызванных воздействием ионизирующей радиации. Экспериментальные исследования под ред. проф. Д. И. Закутинского (Москва: Медгиз, 1959).

4. Руководство по радиационной гематологии. Cовместное издательство МАГАТЭ, ВОЗ (Москва: Медицина, 1974) 328 с.

5. Пинчук Л. Б., Родионова Н. К., Липская А. И., Глузман Д. Ф. Эксперим. онкология 18 (1996) 109.

6. Гольдберг Е. Д., Гольдберг Д. И. Атлас микрофотографий костного мозга при острой лучевой болезни и действии цитостатических препаратов (Москва: Медицина, 1973) 144 с.

7. Маслова К. Н., Материй Л. Д., Ермакова О. Б., Таскаев А. И. Атлас патоморфологических изменений у полевок-экономок из очагов локального радиоактивного загрязнения (Санкт-Петербург: Наука, 1994) 192 с.

8. Глузман Д. Ф., Мутэ А., Пинчук Л. Б. и др. Эксперим. онкология 14 (1992) 41.