Ядерна фізика та енергетика Nuclear Physics and Atomic Energy   ISSN: 1818-331X (Print), 2074-0565 (Online)   Publisher: Institute for Nuclear Research of the National Academy of Sciences of Ukraine   Languages: Ukrainian, English   Periodicity: 4 times per year   Open access peer reviewed journal

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V. A. Kurochkina^*, L. K. Bezdrobna, T. V. Tsyhanok, M. V. Strilchuk, I. A. Maliuk

Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine

^*Corresponding author. E-mail address: knitel@ukr.net

Abstract: The linear dependence of the yield of unstable chromosomal aberrations in human lymphocytes on the dose of prolonged external and/or internal irradiation of peripheral blood samples by ¹³⁷Cs in the dose range of 0.09 - 0.54 Gy in vitro is presented. The higher cytogenetic efficiency of internal ¹³⁷Cs irradiation is shown in comparison with external. It is shown that the cytogenetic efficiency of ¹³⁷Cs in blood contamination is caused by influence on cells not only in the mitotic rest phase but during proliferation, within intracellular radioactivity through their cultivation. It is proposed to use the presented dose dependences of the yield of chromosomal aberrations in lymphocytes in vitro for human biological dosimetry during radiation accidents associated with prolonged external exposure or ¹³⁷Cs incorporation to the body as a supplement to the results of physical dosimetry.

Keywords: ¹³⁷Cs external irradiation, internal irradiation, human blood lymphocytes, chromosomal aberrations, biological dosimetry.

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