Nuclear Physics and Atomic Energy

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Nuclear Physics and Atomic Energy

  ISSN: 1818-331X (Print), 2074-0565 (Online)
  Publisher: Institute for Nuclear Research of the National Academy of Sciences of Ukraine
  Languages: Ukrainian, English, Russian
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Nucl. Phys. At. Energy 2015, volume 16, issue 3, pages 277-281.
Section: Radiobiology and Radioecology.
Received: 30.06.2015; Accepted: 30.07.2015; Published online: 12.10.2015.
PDF Full text (ua)
https://doi.org/10.15407/jnpae2015.03.277

Ñytogenetic effects in the bone marrow of rats with long-term ingestion of 131I

Î. A. Sova*

Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine

*Corresponding author. E-mail address: olenasova.ua@gmail.com

Abstract: Cytogenetic effects in the rats bone marrow after long-term ingestion of 131² were studied. Significant increase of chromosomal aberrations by dicentric aberrations with and without fragments, acentric fragments, atypical chromosomes and polyploidies was found. Chromatid-type aberrations in exposed animals were present at the same level as in the control group.

Keywords: isotope 131I, dose formation, bone marrow cells, chromosomal aberrations, polyploidy.

References:

1. I.Ya. Vasilenko, O.I. Vasilenko. Radioactive iodine. Energy: Economics, Technology, Ecology 5 (2003) 57. (Rus)

2. I.Ya. Vasilenko. Radiation safety of iodine isotopes. Atomic Energy 63(4) (1987) 244. (Rus)

3. O.I. Vasilenko. Radiation Ecology (Moskva: Medicine, 2004) 216 p. (Rus)

4. L.A. Ilyin. In: Radioactive Iodine in the Problem of Radiation Safety (Moskva: Atomizdat, 1972) p. 27. (Rus)

5. V.M. Kolobashkin, P.M. Rubtsov, P.A. Ruzhanskij, V.D. Sidorenko. Radiation Characteristics of Irradiated Nuclear Fuel: Handbook (Moskva: Energoatomizdat, 1983) 374 p. (Rus)

6. Thyroid. Fundamental Aspects. Eds. A.I. Kubarko and S. Yamashita (Minsk-Nagasaki, 1998) 368 p. (Rus)

7. G.K. Korolev. In: Distribution, Metabolism and Kinetics of the Biological Effects of Radioactive Iodine Isotopes: Collection of Papers. Eds. L.A. Ilyin, Yu.I. Moskalev (Moskva: Medicine, 1970) p. 36. (Rus)

8. A.S. Monahov. Cytogenetic investigation of the effects of incorporated radionuclides in the blood lymphocytes of animals. Extended Abstract of PhD Dissertation (Biology) (Leningrad, 1984) 18 p. (Rus).

9. O.A. Sova, ².P. Drozd. Dose formation and hematologic effects with prolonged internal exposure of rats y isotope 131I. Yaderna Fizyka ta Energetyka (Nucl. Phys. At. Energy) 15(4) (2014) 359. (Ukr) https://jnpae.kinr.kyiv.ua/15.4/Articles_PDF/jnpae-2014-15-0359-Sova.pdf

10. E.A. Demina, I.R. Bariljak, M.A. Pilinskaja. Dictionary of Radiation Cytogenetics (Kyiv: V³snyk, 1994) 125 p. (Rus)

11. E.V. Hulse. Recovery after Irradiation and its Relation to Other Aspects of Haemopoiesise. British Journal of Haematology 9 (1963) 376. https://doi.org/10.1111/j.1365-2141.1963.tb06562.x