Nuclear Physics and Atomic Energy

Ядерна фізика та енергетика
Nuclear Physics and Atomic Energy

  ISSN: 1818-331X (Print), 2074-0565 (Online)
  Publisher: Institute for Nuclear Research of the National Academy of Sciences of Ukraine
  Languages: Ukrainian, English, Russian
  Periodicity: 4 times per year

  Open access peer reviewed journal

 Home page   About 
Nucl. Phys. At. Energy 2015, volume 16, issue 3, pages 277-281.
Section: Radiobiology and Radioecology.
Received: 30.06.2015; Accepted: 30.07.2015; Published online: 12.10.2015.
PDF Full text (ua)
https://doi.org/10.15407/jnpae2015.03.277

Сytogenetic effects in the bone marrow of rats with long-term ingestion of 131I

О. A. Sova*

Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine

*Corresponding author. E-mail address: olenasova.ua@gmail.com

Abstract: Cytogenetic effects in the rats bone marrow after long-term ingestion of 131І were studied. Significant increase of chromosomal aberrations by dicentric aberrations with and without fragments, acentric fragments, atypical chromosomes and polyploidies was found. Chromatid-type aberrations in exposed animals were present at the same level as in the control group.

Keywords: isotope 131I, dose formation, bone marrow cells, chromosomal aberrations, polyploidy.

References:

1. I.Ya. Vasilenko, O.I. Vasilenko. Radioactive iodine. Energy: Economics, Technology, Ecology 5 (2003) 57. (Rus)

2. I.Ya. Vasilenko. Radiation safety of iodine isotopes. Atomic Energy 63(4) (1987) 244. (Rus)

3. O.I. Vasilenko. Radiation Ecology (Moskva: Medicine, 2004) 216 p. (Rus)

4. L.A. Ilyin. In: Radioactive Iodine in the Problem of Radiation Safety (Moskva: Atomizdat, 1972) p. 27. (Rus)

5. V.M. Kolobashkin, P.M. Rubtsov, P.A. Ruzhanskij, V.D. Sidorenko. Radiation Characteristics of Irradiated Nuclear Fuel: Handbook (Moskva: Energoatomizdat, 1983) 374 p. (Rus)

6. Thyroid. Fundamental Aspects. Eds. A.I. Kubarko and S. Yamashita (Minsk-Nagasaki, 1998) 368 p. (Rus)

7. G.K. Korolev. In: Distribution, Metabolism and Kinetics of the Biological Effects of Radioactive Iodine Isotopes: Collection of Papers. Eds. L.A. Ilyin, Yu.I. Moskalev (Moskva: Medicine, 1970) p. 36. (Rus)

8. A.S. Monahov. Cytogenetic investigation of the effects of incorporated radionuclides in the blood lymphocytes of animals. Extended Abstract of PhD Dissertation (Biology) (Leningrad, 1984) 18 p. (Rus).

9. O.A. Sova, І.P. Drozd. Dose formation and hematologic effects with prolonged internal exposure of rats y isotope 131I. Yaderna Fizyka ta Energetyka (Nucl. Phys. At. Energy) 15(4) (2014) 359. (Ukr) https://jnpae.kinr.kyiv.ua/15.4/Articles_PDF/jnpae-2014-15-0359-Sova.pdf

10. E.A. Demina, I.R. Bariljak, M.A. Pilinskaja. Dictionary of Radiation Cytogenetics (Kyiv: Vіsnyk, 1994) 125 p. (Rus)

11. E.V. Hulse. Recovery after Irradiation and its Relation to Other Aspects of Haemopoiesise. British Journal of Haematology 9 (1963) 376. https://doi.org/10.1111/j.1365-2141.1963.tb06562.x