Nuclear Physics and Atomic Energy

Ядерна фізика та енергетика
Nuclear Physics and Atomic Energy

  ISSN: 1818-331X (Print), 2074-0565 (Online)
  Publisher: Institute for Nuclear Research of the National Academy of Sciences of Ukraine
  Languages: Ukrainian, English
  Periodicity: 4 times per year

  Open access peer reviewed journal

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Nucl. Phys. At. Energy 2009, volume 10, issue 4, pages 403-408.
Section: Radiobiology and Radioecology.
Received: 24.11.2009; Published online: 30.12.2009.
PDF Full text (ua)
https://doi.org/10.15407/jnpae2009.04.403

Peroxidation of blood plasma lipids after various regimes of external irradiation of rats by 60Co gamma-rays

M. Vatankhan1, A. I. Lypska2, Ya. I. Serkiz2

1National Research Center for Radiation Medicine of National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine 2Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine

Abstract: Peroxidation products of lipids in blood plasma of laboratory rats are studied after one-time, fractional and long-term external irradiation of the rats by 60Co gamma-rays. It was found that different modes of a total external irradiation of rats lead to prominent features of dynamics and dose dependences of radio gene changes of the content of peroxidation products of lipids in blood plasma. It was shown that fractional irradiation is less effective for an organism, whereas long-term irradiation causes essentially big radiation induced changes than one-time action of radiation.

Keywords: rats, 60Co gamma-rays, one-time irradiation, fractional and long-term irradiation, diene conjugates, malonic dialdehyde.

References:

1. Владимиров Ю. А., Арчаков А. И. Перекисное окисление липидов биологических мембран (Москва: Наука, 1972) 259 с.

2. Бурлакова Е. Б., Голощапов А. Н., Горбунова Н. В. и др. Особенности биологического действия малых доз облучения. Радиац. биол. Радиоэкол. 36 (1996) 610.

3. Серкиз Я. И., Пинчук В. Г., Пинчук Л. Б. и др. Радиобиологические аспекты аварии на Чернобыльской АЭС. Под ред. В. А. Барабой (Київ: Наук. думка, 1992) 172 с.

4. Гаврилов В. Б., Гаврилова Л. Б., Хмара Н. Ф. Измерение диеновых конъюгатов в плазме крови по УФ-поглощению гептановых и изопропиленовых экстрактов. Лаб. дело 2 (1988) 60.

5. Стальная И. Д. Методы определения некоторых продуктов перекисного окисления липидов в тканях животных. Современные методы в биохимии (1977) c. 62.