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Ядерна фізика та енергетика
ISSN:
1818-331X (Print), 2074-0565 (Online) |
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Radiologically induced changes of lipide content in blood plasma, after fractional and prolonged irradiation of laboratorial rats by 60Co γ-quanta
Manouchehr Vatankhah1, Y. I. Serkiz2
1State Institution "National Research Center for Radiation Medicine of National Academy of Medical Sciences of Ukraine", Kyiv, Ukraine
2Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine
Abstract: It is discovered that different forms of rat irradiation lead to typical features in dynamics and portioned dependencies of radiogenic changes of lipids content in blood plasma. It is shown that fractional irradiation is more spareful to organism, and prolonged will call significally more radiologically initiated changes, than one-time irradiation. It is set for the first time that on different stages of organism reaction development, examined variables of lipids content, showed different sensitivity to specific doses and forms of irradiation. This testifies that on different stages of organism reaction different components can implement their participation in lipids peroxyding with different speed.
Keywords: γ-quantum 60Co, rats, fractioned and prolonged irradiation, blood lipids.
References:1. Серкиз Я. И., Пинчук В. Г., Пинчук Л. Б. и др. Радиобиологические аспекты аварии на Чернобыльской АЭС (Київ: Наук. думка, 1992) 172 с.
2. А. І. Липська, Я. І. Серкіз. Природа та закономірності радіаційного канцерогенезу. Зб. наук. праць Ін-ту ядерних досл. 5 (2004) 114. https://jnpae.kinr.kyiv.ua/05.2/Articles_PDF/jnpae-2004-05-2-114.pdf
3. Кейтс М. Техника липидологии (Москва: Мир, 1975) 214 с.
4. Abell L. L., Levy B. B., Brodie B. B. A simplified method for the estimation of total cholesterol in serum and demonstration of its specificity. J. Biol. Chem. 195 (1952) 357. https://doi.org/10.1016/S0021-9258(19)50907-3
5. Carlson L. A. Determination of serum triglycerides. J. Atherosclerosis Res. 3 (1963) 334. https://doi.org/10.1016/S0368-1319(63)80012-5
6. Vaskovsky V. E., Svetashev V. I. Phospholipid spray reagents. J. Chromatogr. A 65 (1972) 451. https://doi.org/10.1016/S0021-9673(00)92571-8
7. Липська А. І. Дозоутворення, природа ранніх та ризики віддалених ефектів у тварин за тривалої дії радіонуклідів чорнобильського викиду: Автореф. дис. … докт. біол. наук (Київ, 2008) 44 с.