![]() |
Ядерна фізика та енергетика
ISSN:
1818-331X (Print), 2074-0565 (Online) |
Home page | About |
The optimized nuclear microprobe with an external proton beam
S. O. Lebed1, O. G. Kukharenko1, O. O. Veselov2, J. Lekki2, Z. Stachura2
1Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine
2Institute of Nuclear Physics, Kraków, Poland
Abstract: On the basis of numerical simulation, using the SRІM program and author's programs (INITBEAM, DEGRADBEAM), close optimal structure and geometrical parameters of an exit device of the nuclear microprobe (NMP) with the external beam of ions are determined. Thin films-windows (Sі3N4, Mylar, Kapton or Al) of thickness of 0.2 - 10 microns are used in the exit device. The obtained results allow carrying out the optimized choice of geometrical parameters of the device and films-windows to pass to atmosphere (normal conditions) high energy (2.5 МeV) proton microbeam with the purpose to achieve the minimal degradation of the main ion-optical parameters of the probe on the sample surface. Calculations were used to develop design of the exit device, specialized for a precision irradiation of microscopic samples (living cells) by single ions, of Kraków NMP with the external beam of ions. Some features of this device are discussed in article.
References:1. Fischer B. E., Metzger S. Aiming fit hit verification in single ion techniques. Nuclear Instruments and Methods in Physics Research B 104 (1995) 7. https://doi.org/10.1016/0168-583X(95)00384-3
2. Calligaro T., Dran J. -C., Hamon H. et al. An external milli-beam for archaeometric applications on the AGLAE IBA facility of the Louvre museum. Nuclear Instruments and Methods in Physics Research B 136-138 (1998) 339. https://doi.org/10.1016/S0168-583X(97)00703-9
3. Michelet C., Moretto Ph., Laurent G. et al. Measurement of lateral straggling using a microbeam. Nuclear Instruments and Methods in Physics Research B 181 (2001) 157. https://doi.org/10.1016/S0168-583X(01)00546-8
4. Kamiya T., Sakai T., Oikawa M. STIM imaging mammalian cell samples before micro-PIXE analyses in air environment at Jaeri Takasaki light ion microbeam system. International Journal of PIXE 9 (1999) 217. https://doi.org/10.1142/S0129083599000310
5. Sugimoto A., Ishii K., Matsuyama S. et al. Application of micro-PIXE camera to elemental analysis of a single cell. International Journal of PIXE 9 (1999) 151. https://doi.org/10.1142/S0129083599000243
6. Sakai T., Naitoh Y., Kamiya T., Kobayashi Y. Single Ion Hitting to Living Samples. Nuclear Instruments and Methods in Physics Research B 158 (1999) 250. https://doi.org/10.1016/S0168-583X(99)00529-7
7. Lekki J., Cholewa M., Dutkiewicz E. et al. IFJ Project of Single Proton Irradiation of Biological Cells. Report No 1915/B SPH (The Henryk Niewodniczański Institute of Nuclear Physics, Kraków, Poland. 2002). www.ifj.edu.pl/reports/2002.html
8. Polak W., Lekki J., Gryboś J. et al. Testing the efficiency of the Si3N4 membranes for charged particles registration. Nucleonika 48 (2003) 25.
9. Cholewa M., Fischer B. E., Heiß M. Preparatory Experiments for a Second-Generation Radiation-Biological Single Hit Facility. GSI, Material Research, Planckstr.1, D - 64291 Darmstadt, SHIM (2002).
10. Інформація з джерел:
11. Ziegler J. F., Biersack J. P., Liimark U. The Stopping and Range of Ions in Matter (Pergamon Press, 1985) Vol. 1. SRIM program version 2003. http://www.srim.org
12. Breese M., Jamieson D., King P. Materials Analysis Using a Nuclear Microprobe (New York: Wiley, 1996) p. 367.
13. Бор Н. Теория торможения заряженных частиц при их прохождении через вещество. Избранные научные труды. В 2-х т. (Москва: Наука, 1970) Т. 1, c. 63.
14. Traxel K., Arndt P., Bohsung J. et al. The new Heidelberg proton microprobe: The success of minimal concept. Nuclear Instruments and Methods in Physics Research B 104 (1995) 19. https://doi.org/10.1016/0168-583X(95)00396-7
15. Інформація з вебсторінки: http://www.physikinstrumente.de
16. Barone-Nugent E. D., Barty A., Nugent K. A. J. Microscopy 206 (2002) 194. https://doi.org/10.1046/j.1365-2818.2002.01027.x
17. Інформація з вебсторінки: http://www.iatia.com.au
18. Veselov O., Lekki J., Polak W. et al. The recognition of biological cells utilizing quantitative phase microscopy system. Proc. of ICNMTA-2004 (Cavtat, Croatia, September 2004);
Nuclear Instruments and Methods in Physics Research B 231 (2005) 212. https://doi.org/10.1016/j.nimb.2005.01.059